Whole Genome Sequencing in Reproductive Medicine: Clinical Utility, Ethical Considerations, and Future Directions Presented by: 1. Sofia Horan, MS, CGC 2. Olivia Maher Trocki, MS, CGC 3. Allan Fisher, MD 4. Maria Katz, MSc, LCGC 5. Kathryn J. Gray, MD, PhD Whole genome sequencing (WGS) is rapidly expanding within reproductive care, offering new insights—and new uncertainties—across both preimplantation and prenatal settings. This session will explore the clinical utility, technical landscape, and ethical considerations of WGS through real-world case studies and interactive debate. Drawing on perspectives from maternal fetal medicine, reproductive genetics, and research, panelists will examine how WGS results shape decision-making and where gaps remain in guidance and equity. Special attention will be given to issues of access, systemic bias, and how to responsibly integrate WGS into care models that are inclusive and patient-centered. Learning Objectives: 1. Evaluate the clinical utility of WGS at different points in the reproductive journey. 2. Identify ethical implications of the use of WGS in the prenatal period and the preconception period. 3. Delineate the current technical state of WGS by examining similarities and differences in technical methodologies, potential results, and clinical actionability between preconception and pregnancy. The National Society of Genetic Counselors (NSGC) has authorized National Society of Genetic Counselors (NSGC) to offer up to 1.5 Category 1 contact hours for Whole Genome Sequencing in Reproductive Medicine: Clinical Utility, Ethical Considerations, and Future Directions. The American Board of Genetic Counseling (ABGC) will accept CEUs earned at this program for the purposes of genetic counselor certification and recertification. Successful Completion: 1. View recording 2. Pass quiz 3. Complete survey